The Oscar winner will appear on Monday October 22.
Tonight Denton has more good guests including Ewan McGregor and friend Charley Boorman who will talk about their world travels on motorbikes.
Pamela Stephenson also appears.
Winner of of an Academy Award (2007), four BAFTAs, and three Golden Globe Awards (two in in 2007), and named Best Actress at the 2006 Venice Film Festival for her portrayal of Queen Elizabeth II, Mirren is one of the most admired actresses of our time. Her career has spanned four decades – she made her first film in 1967.
After an already impressive theatre and film career, Mirren came to the attention of many television viewers as Detective Supintendent Jane Tennison in the very successful British TV drama series Prime Suspect.
Enough Rope with Andrew Denton airs 9:35pm on ABC TV.