The move comes despite hopes for a sixth season, including an unresolved storyline for its lead character Annie Walker (Piper Perabo).
The reason is attributed to rising costs in talent fees and grander locations, falling Overnight numbers, and USA finding it hard to monetise low demo numbers.
Deadline notes USA is also going through a slate changeover, parting with veterans White Collar and Covert Affairs and gearing up to launch a slew of new dramas: Dig, Complications and Mr. Robot, with four more drama pilots — Colony, Queen Of The South, Evil Men and Stanistan — awaiting word on a series pickup.
Suits, Royal Pains and Graceland have all been previously renewed.
Covert Affairs screens in Australia on Seven.