Kelsey Grammer, Stephen Moyer in Killing Jesus telemovie.

Kelsey Grammer as King Herod? Stephen Moyer as Pontius Pilate?

Yes, it’s all part of National Geographic Channel’s telemovie Killing Jesus, based on the book by Bill O’Reilly and Martin Dugard.

The telemovie will chronicle the life of Jesus through the retelling of political, social and historical conflicts during the Roman Empire. O’Reilly has previously penned similar studies of historical deaths including John F. Kennedy and Abraham Lincoln.

“The film Killing Jesus will break new ground in chronicling the life of the most famous human being who ever lived,” said O’Reilly, who also serves as an executive producer. “The superb cast and script reflect much thought and research. Viewers are in for something very different and very special.”

Haaz Sleiman (“The Visitor”) will portray the title character Jesus, with Rufus Sewell (“Hercules”) as Caiaphas, high priest of Jerusalem and conspirator in Jesus’ death; Emmanuelle Chriqui (“Entourage”) as Herodia, ex-wife of Herod II and wife of his brother Antipas, who manipulated her husband and daughter into killing John the Baptist; Eoin Macken (“The Night Shift”) as Antipas, the tetrarch of Galilee and Perea and co-conspirator in Jesus’ death; John Rhys Davies (“Indiana Jones”) as Annas, a high priest in Jerusalem who first questioned Jesus and his teachings; Abhin Galeya as John the Baptist, who was considered a prophet and arrested and killed by Antipas; and Stephanie Leonidas (“Defiance”) as Salome, daughter of Herod II and Herodias.

Rounding out the cast will be Aneurin Barnard (“The White Queen”) as James, one of Jesus’ 12 apostles; Vernon Dobtcheff (“Before Sunset”) as Isaiah, the prophet whom King Herod claimed came to him in a dream and prophesied his death; Tamsin Egerton (“The Look of Love”) as Claudia, the wife of Pontius Pilate; John Lynch (“Sliding Doors”) as Nicodemus, a Pharisee and member of the high court in Israel, who was sympathetic to Jesus; Joe Doyle (“Reign”) as Judas, the apostle who eventually betrayed Jesus; and Alexis Rodney (“Guardians of the Galaxy”) as Simon (Peter), one of Jesus’ 12 apostles and confidant.

The project films this fall under the guidance of U.K.-based director Chris Menaul, with a teleplay from Oscar and Emmy Award winning screenwriter Walon Green.

Based on the best-selling book by O’Reilly and Martin Dugard, the film will chronicle the life of Jesus of Nazareth through the retelling of the intense political, social and historical conflicts during the Roman Empire that ultimately led to his death. Jesus lived at a time when the Roman Empire dominated the Western world, and he made powerful enemies while preaching a philosophy of peace and love. Today, more than 2.2 billion people follow his teachings, but the intimate historical details of the time usually remain secondary to his story.

Killing Jesus marks the third collaboration for NGC, Scott Free Productions and Bill O’Reilly, following Killing Lincoln and the Emmy nominated Killing Kennedy.

It will air on Nat Geo in 2015.